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Androgen-independent prostate cancer cells acquire the complete steroidogenic potential of synthesizing testosterone from cholesterol

The proliferation and differentiation of normal prostate epithelial cells depends upon the action of androgens produced by the testis. Prostate cancers retain the ability to respond to androgens in the initial stages of cancer development, but progressively become independent of exogenous androgens...

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Detalhes bibliográficos
Main Authors: Dillard, Paulette R., Lin, Ming-Fong, Khan, Shafiq A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802176/
https://ncbi.nlm.nih.gov/pubmed/18782595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2008.08.013
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