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Microcapsules and Transdermal Patch: A Comparative Approach for Improved Delivery of Antidiabetic Drug

Glibenclamide (GL)-loaded microcapsules (MC) and transdermal patches (TDP) were formulated and in vitro and in vivo parameters compared to find out the best route of drug administration. The formulation TDP1 having a drug–polymer ratio 1:1 showed comparatively higher GL release and better permeation...

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Detalhes bibliográficos
Main Authors: Mishra, Manoj K., Ray, Debajyoti, Barik, Bhakti B.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802161/
https://ncbi.nlm.nih.gov/pubmed/19629706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9289-z
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