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Formulation of Dacarbazine-Loaded Cubosomes—Part I: Influence of Formulation Variables

The purpose of this study was to investigate the combined influence of three-level, three-factor variables on the formulation of dacarbazine (a water-soluble drug) loaded cubosomes. Box–Behnken design was used to obtain a second-order polynomial equation with interaction terms to predict response va...

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Autors principals: Bei, Di, Marszalek, Jacob, Youan, Bi-Botti C.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802140/
https://ncbi.nlm.nih.gov/pubmed/19669896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9293-3
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