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Development of an Ex Vivo Method for Evaluation of Precorneal Residence of Topical Ophthalmic Formulations

This paper describes the development of an ex vivo perfusion method for the evaluation of topical ophthalmic formulations. The perfusion system developed consisted of a perfusion chamber, two precision pumps to control the in/out flow rates to simulate the tear flow rate, and a fluorescence microsco...

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Autors principals: Liu, Quan, Wang, Youmin
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802139/
https://ncbi.nlm.nih.gov/pubmed/19521781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9266-6
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