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Accelerated Ovarian Aging in the Absence of the Transcription Regulator TAF4B in Mice

The mammalian ovary is unique in that its reproductive life span is limited by oocyte quantity and quality. Oocytes are recruited from a finite pool of primordial follicles that are usually exhausted from the ovary during midadult life. If regulation of this pool is perturbed, the reproductive capac...

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Bibliographic Details
Main Authors: Lovasco, Lindsay A., Seymour, Kimberly A., Zafra, Kathleen, O'Brien, Colin W., Schorl, Christoph, Freiman, Richard N.
Format: Artigo
Language:Inglês
Published: Society for the Study of Reproduction, Inc. 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802112/
https://ncbi.nlm.nih.gov/pubmed/19684329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.077495
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