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The cytoplasmic domain of Escherichia coli leader peptidase is a "translocation poison" sequence.

Leader peptidase is an integral, transmembrane protein of the plasma membrane of Escherichia coli. Its membrane assembly requires its internal, uncleaved signal sequence, its large periplasmic carboxyl-terminal region, and an apolar domain that is known as a "hydrophobic helper." We now show that th...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: von Heijne, G, Wickner, W, Dalbey, R E
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1988
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280209/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3285342/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.10.3363
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