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Caspase activation in transgenic mice with Alzheimer-like pathology: results from a pilot study utilizing the caspase inhibitor, Q-VD-OPh

Despite the wealth of evidence supporting the activation of caspases in Alzheimer's disease (AD), chronic administration of a caspase inhibitor has never been tested in any animal model system. The purpose of the current report was to identify a suitable animal model that displays caspase activ...

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Detalhes bibliográficos
Main Authors: Rohn, Troy T., Kokoulina, Polina, Eaton, Cody R., Poon, Wayne W.
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802048/
https://ncbi.nlm.nih.gov/pubmed/20057974
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