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Effect of the mechanical activation on size reduction of crystalline acetaminophen drug particles

The decrease in particle size may offer new properties to drugs. In this study, we investigated the size reduction influence of the acetaminophen (C(8)H(9)O(2)N) particles by mechanical activation using a dry ball mill. The activated samples with the average size of 1 μm were then investigated in di...

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Détails bibliographiques
Auteurs principaux: Biazar, Esmaeil, Beitollahi, Ali, Rezayat, S Mehdi, Forati, Tahmineh, Asefnejad, Azadeh, Rahimi, Mehdi, Zeinali, Reza, Ardeshir, Mahmoud, Hatamjafari, Farhad, Sahebalzamani, Ali, Heidari, Majid
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802041/
https://ncbi.nlm.nih.gov/pubmed/20054432
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