A carregar...
Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognition
Pumilio 2 (Pum2) interacts with the 3′ UTR-containing pumilio binding element (PBE) of RINGO/SPY mRNA to repress translation in Xenopus oocytes. Here, we show that Pum2 also binds directly to the 5′ 7mG cap structure; in so doing, it precludes eIF4E from binding the cap. Using deletion analysis, we...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802031/ https://ncbi.nlm.nih.gov/pubmed/19933321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1884610 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|