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Analysis of the regulatory phosphorylation site in Acanthamoeba myosin IC by using site-directed mutagenesis

The actin-activated ATPase activity of Acanthamoeba myosin IC is stimulated 15- to 20-fold by phosphorylation of Ser-329 in the heavy chain. In most myosins, either glutamate or aspartate occupies this position, which lies within a surface loop that forms part of the actomyosin interface. To investi...

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Библиографические подробности
Главные авторы: Wang, Zhen-Yuan, Wang, Fei, Sellers, James R., Korn, Edward D., Hammer, John A.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1998
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC28020/
https://ncbi.nlm.nih.gov/pubmed/9860946
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