IASH - ERK1/2 ACTIVATION, VIA DOWNREGULATION OF MKP-1, MEDIATES SEX-DIFFERENCES IN DOCA-SALT HYPERTENSION VASCULAR REACTIVITY

ERK1/2 has been reported to play a role in vascular dysfunction associated with mineralocorticoid hypertension. We hypothesized that compared to females, an upregulation of ERK1/2 signaling in the vasculature of male rats contributes to augmented contractile responses in mineralocorticoid hypertensi...

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Detalhes bibliográficos
Main Authors: Giachini, Fernanda R., Sullivan, Jennifer C., Lima, Victor V., Carneiro, Fernando S., Fortes, Zuleica B., Pollock, David M., Carvalho, Maria Helena C., Webb, R. Clinton, Tostes, Rita C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801880/
https://ncbi.nlm.nih.gov/pubmed/19901158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.140459
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