Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes

Transplantation of human embryonic stem cell-derived cardiomyocytes (hESC-CM) for cardiac regeneration is hampered by the formation of fibrotic tissue around the grafts, preventing electrophysiological coupling. Investigating this process, we found that: (1) beating hESC-CM in vitro are embedded in...

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Detalhes bibliográficos
Main Authors: van Laake, L. W., van Donselaar, E. G., Monshouwer-Kloots, J., Schreurs, C., Passier, R., Humbel, B. M., Doevendans, P. A., Sonnenberg, A., Verkleij, A. J., Mummery, Christine L.
Formato: Artigo
Idioma:Inglês
Publicado em: SP Birkhäuser Verlag Basel 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801836/
https://ncbi.nlm.nih.gov/pubmed/19844658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-009-0179-z
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