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Propofol induces ERK-dependant expression of c-Fos and Egr-1 in neuronal cells

This study explored the effects of propofol on c-Fos and Egr-1 in neuroblastoma (N2A) cells. We demonstrate that propofol induced the expression of c-Fos and Egr-1 within 30 and 60 min of exposure time. At 16.8 µM concentration, propofol induced a 6 and 2.5-fold expression of c-Fos and Egr-1, respec...

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Detalhes bibliográficos
Main Authors: Kidambi, Srivatsan, Yarmush, Joel, Fong, Wayne, Kamath, Sangeetha, SchianodiCola, Joseph, Nahmias, Yaakov
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801809/
https://ncbi.nlm.nih.gov/pubmed/19349923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e328329a449
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