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IL-23 signaling enhances Th2 polarization and regulates allergic airway inflammation

IL-23/IL-17 axis is an important regulator in various inflammatory diseases. However, the role of IL-23 in allergic airway inflammation is not well understood. In this study, we show that in an allergen-induced asthma model, mice with transgenic overexpression of IL-23R exhibited increased airway in...

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Autori principali: Peng, Juan, Yang, Xuexian O., Chang, Seon Hee, Yang, Jiong, Dong, Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801763/
https://ncbi.nlm.nih.gov/pubmed/19935773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2009.128
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