Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120.

Antisera to recombinant human immunodeficiency virus (HIV) proteins containing the entire envelope, gp160, or the central portion of the envelope, PB1, can inhibit fusion of virally infected cells in culture. This fusion inhibition is HIV-variant specific--that is, anti-gp160-IIIB inhibits fusion of...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Rusche, J R, Javaherian, K, McDanal, C, Petro, J, Lynn, D L, Grimaila, R, Langlois, A, Gallo, R C, Arthur, L O, Fischinger, P J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1988
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280171/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2452447/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.9.3198
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