Multi-Platform Whole-Genome Microarray Analyses Refine the Epigenetic Signature of Breast Cancer Metastasis with Gene Expression and Copy Number

BACKGROUND: We have previously identified genome-wide DNA methylation changes in a cell line model of breast cancer metastasis. These complex epigenetic changes that we observed, along with concurrent karyotype analyses, have led us to hypothesize that complex genomic alterations in cancer cells (de...

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Bibliographic Details
Main Authors: Andrews, Joseph, Kennette, Wendy, Pilon, Jenna, Hodgson, Alexandra, Tuck, Alan B., Chambers, Ann F., Rodenhiser, David I.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801616/
https://ncbi.nlm.nih.gov/pubmed/20084286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008665
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