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Nonrandom X chromosome inactivation in B cells from carriers of X chromosome-linked severe combined immunodeficiency.

X chromosome-linked severe combined immunodeficiency (XSCID) is characterized by markedly reduced numbers of T cells, the absence of proliferative responses to mitogens, and hypogammaglobulinemia but normal or elevated numbers of B cells. To determine if the failure of the B cells to produce immunog...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Conley, M E, Lavoie, A, Briggs, C, Brown, P, Guerra, C, Puck, J M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280149/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2896355/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.9.3090
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