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Sequence analysis of the MYC oncogene involved in the t(8;14)(q24;q11) chromosome translocation in a human leukemia T-cell line indicates that putative regulatory regions are not altered.

We have cloned the translocation-associated and homologous normal MYC alleles from SKW-3, a leukemia T-cell line with the t(8;14)(q24;q11) translocation, and determined the sequence of the MYC oncogene first exon and flanking 5' putative regulatory regions. S1 nuclease protection experiments utilizi...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Finver, S N, Nishikura, K, Finger, L R, Haluska, F G, Finan, J, Nowell, P C, Croce, C M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280141/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2834731/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.9.3052
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