Enzymatic Activity Is Required for the in Vivo Functions of CARM1

CARM1 is one of nine protein arginine methyltransferases that methylate arginine residues in proteins. CARM1 is recruited by many different transcription factors as a positive regulator. Gene targeting of CARM1 in mice has been performed, and knock-out mice, which are smaller than their wild-type li...

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Bibliographic Details
Main Authors: Kim, Daehoon, Lee, Jaeho, Cheng, Donghang, Li, Jia, Carter, Carla, Richie, Ellen, Bedford, Mark T.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Transcription, Chromatin, and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801243/
https://ncbi.nlm.nih.gov/pubmed/19897492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.035865
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