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Binding to DNA Protects Neisseria meningitidis Fumarate and Nitrate Reductase Regulator (FNR) from Oxygen

Here, we report the overexpression, purification, and characterization of the transcriptional activator fumarate and nitrate reductase regulator from the pathogenic bacterium Neisseria meningitidis (NmFNR). Like its homologue from Escherichia coli (EcFNR), NmFNR binds a 4Fe-4S cluster, which breaks...

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Detalhes bibliográficos
Main Authors: Edwards, James, Cole, Lindsay J., Green, Jasper B., Thomson, Melanie J., Wood, A. Jamie, Whittingham, Jean L., Moir, James W. B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801238/
https://ncbi.nlm.nih.gov/pubmed/19917602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.057810
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