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C-reactive Protein Exists in an NaCl Concentration-dependent Pentamer-Decamer Equilibrium in Physiological Buffer

C-reactive protein (CRP) is an acute phase protein of the pentraxin family that binds ligands in a Ca(2+)-dependent manner, and activates complement. Knowledge of its oligomeric state in solution and at surfaces is essential for functional studies. Analytical ultracentrifugation showed that CRP in 2...

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Hlavní autoři: Okemefuna, Azubuike I., Stach, Lasse, Rana, Sudeep, Ziai Buetas, Akim J., Gor, Jayesh, Perkins, Stephen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801231/
https://ncbi.nlm.nih.gov/pubmed/19903811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.044495
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