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Membrane depolarization and carbamoylcholine stimulate phosphatidylinositol turnover in intact nerve terminals.

Synaptosomes, purified from rat cerebral cortex, were prelabeled with [3H]inositol to study phosphatidylinositol turnover in nerve terminals. Labeled synaptosomes were either depolarized with 40 mM K+ or exposed to carbamoylcholine (carbachol). K+ depolarization increased the level of inositol phosp...

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Bibliographic Details
Main Authors: Audigier, S M, Wang, J K, Greengard, P
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC280099/
https://ncbi.nlm.nih.gov/pubmed/3357896
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