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Concerted Interconversion between Ionic Lock Substates of the β(2) Adrenergic Receptor Revealed by Microsecond Timescale Molecular Dynamics

The recently solved crystallographic structures for the A(2A) adenosine receptor and the β(1) and β(2) adrenergic receptors have shown important differences between members of the class-A G-protein-coupled receptors and their archetypal model, rhodopsin, such as the apparent breaking of the ionic lo...

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Detalhes bibliográficos
Main Authors: Romo, Tod D., Grossfield, Alan, Pitman, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800975/
https://ncbi.nlm.nih.gov/pubmed/20074514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.046
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