Binding and Cleavage of E. coli HUβ by the E. coli Lon Protease

The Escherichia coli Lon protease degrades the E. coli DNA-binding protein HUβ, but not the related protein HUα. Here we show that the Lon protease binds to both HUβ and HUα, but selectively degrades only HUβ in the presence of ATP. Mass spectrometry of HUβ peptide fragments revealed that region K18...

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Detalhes bibliográficos
Main Authors: Liao, Jiahn-Haur, Lin, Yu-Ching, Hsu, Jowey, Lee, Alan Yueh-Luen, Chen, Tse-An, Hsu, Chun-Hua, Chir, Jiun-Ly, Hua, Kuo-Feng, Wu, Tzu-Hua, Hong, Li-Jenn, Yen, Pei-Wen, Chiou, Arthur, Wu, Shih-Hsiung
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Protein
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800966/
https://ncbi.nlm.nih.gov/pubmed/20085725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.052
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