Identification of Two Critically Deleted Regions within Chromosome Segment 7q35-q36 in EVI1 Deregulated Myeloid Leukemia Cell Lines

Chromosomal rearrangements involving the EVI1 proto-oncogene are a recurrent finding in myeloid leukemias and are indicative of a poor prognosis. Rearrangements of the EVI1 locus are often associated with monosomy 7 or cytogenetic detectable deletions of part of 7q. As EVI1 overexpression alone is n...

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Detalhes bibliográficos
Main Authors: De Weer, An, Poppe, Bruce, Vergult, Sarah, Van Vlierberghe, Pieter, Petrick, Marjan, De Bock, Robrecht, Benoit, Yves, Noens, Lucien, De Paepe, Anne, Van Roy, Nadine, Menten, Björn, Speleman, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800774/
https://ncbi.nlm.nih.gov/pubmed/20084277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008676
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