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A tissue-specific DNase I-hypersensitive site in a class II A alpha gene is under trans-regulatory control.

Class II major histocompatibility complex molecules are integral membrane glycoproteins whose distribution is limited to certain tissues. To identify the molecular basis for such specificity, the chromatin configuration of the class II A alpha gene was examined in intact nuclei from various cell typ...

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Main Authors: Liou, H C, Polla, B S, Aragnol, D, Leserman, L D, Griffith, I J, Glimcher, L H
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1988
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC280074/
https://ncbi.nlm.nih.gov/pubmed/3258662
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