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Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I.

Escherichia coli Shiga-like toxin I, a close relative of Shiga toxin and a distant relative of the ricin family of plant toxins, inhibits eukaryotic protein synthesis by catalyzing the depurination of adenosine 4324 in 28S rRNA. By comparing the crystallographic structure of ricin with amino acids c...

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Detalhes bibliográficos
Main Authors: Hovde, C J, Calderwood, S B, Mekalanos, J J, Collier, R J
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC280038/
https://ncbi.nlm.nih.gov/pubmed/3357883
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