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Double error shrinkage method for identifying protein binding sites observed by tiling arrays with limited replication
Motivation: ChIP–chip has been widely used for various genome-wide biological investigations. Given the small number of replicates (typically two to three) per biological sample, methods of analysis that control the variance are desirable but in short supply. We propose a double error shrinkage (DES...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2800349/ https://ncbi.nlm.nih.gov/pubmed/19667080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp471 |
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