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Effect of cholera toxin on histamine release from bone marrow-derived mouse mast cells.

Bone marrow-derived mouse mast cells were sensitized with monoclonal mouse IgE antibody and treated with cholera toxin (CT), which ADP-ribosylated the alpha-subunit of the stimulatory guanine nucleotide-binding regulatory protein Gs, prior to challenge with either antigen or thrombin. The CT treatme...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Saito, H, Okajima, F, Molski, T F, Sha'afi, R I, Ui, M, Ishizaka, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1988
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280025/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2451825/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.8.2504
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