Comparison of the substrate specificities and catalytic properties of the sister N-acetylglucosaminyltransferases, GnT-V and GnT-Vb (IX)

N-Acetylglucosaminlyltransferase-V (GnT-V) synthesizes GlcNAcβ1,6Man branched N-glycans both in vitro and in vivo. A paralog, GnT-Vb (or GnT-IX), has also been shown to synthesize both GlcNAcβ1,6Man branched N- and O-glycans. GnT-V is expressed in most human and rodent tissues while GnT-Vb expressio...

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Detalles Bibliográficos
Main Authors: Alvarez-Manilla, Gerardo, Troupe, Karolyn, Fleming, Maria, Martinez-Uribe, Erika, Pierce, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800246/
https://ncbi.nlm.nih.gov/pubmed/19846580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwp158
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