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Sequence context outside the target region influences the effectiveness of miR-223 target sites in the RhoB 3′UTR

MicroRNAs (miRNAs) are 21–22 nucleotide regulatory small RNAs that repress message translation via base-pairing with complementary sequences in the 3′ untranslated region (3′UTR) of targeted transcripts. To date, it is still difficult to find a true miRNA target due to lack of a clear understanding...

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Detalhes bibliográficos
Main Authors: Sun, Guihua, Li, Haitang, Rossi, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800228/
https://ncbi.nlm.nih.gov/pubmed/19850724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp870
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