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An 11-kDa form of human immunodeficiency virus protease expressed in Escherichia coli is sufficient for enzymatic activity.

In order to define the protease domain of human immunodeficiency virus 1, various regions of the pol open reading frame were cloned and expressed in Escherichia coli. Antiserum directed against the conserved retroviral protease active site was used to identify pol precursor and processed species con...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Graves, M C, Lim, J J, Heimer, E P, Kramer, R A
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1988
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3282230/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.8.2449
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