Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes

Maintaining the integrity of sperm DNA is vital to reproduction and male fertility. Sperm contain a number of molecules and pathways for the repair of base excision, base mismatches and DNA strand breaks. The presence of Poly (ADP-ribose) polymerase (PARP), a DNA repair enzyme, and its homologues ha...

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Bibliographic Details
Main Authors: Agarwal, Ashok, Mahfouz, Reda Z, Sharma, Rakesh K, Sarkar, Oli, Mangrola, Devna, Mathur, Premendu P
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800114/
https://ncbi.nlm.nih.gov/pubmed/19961617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-7-143
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