Proteolytic requirements for thrombin activation of anti-hemophilic factor (factor VIII).

Factor VIII functions in the intrinsic pathway of coagulation as the cofactor for factor IXa proteolytic activation of factor X. Proteolytic cleavage is required for activation and may be responsible for inactivation of cofactor activity. To identify which of the multiple cleavages are required for...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Pittman, D D, Kaufman, R J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280010/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3128786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.8.2429
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