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Channel protein engineering: synthetic 22-mer peptide from the primary structure of the voltage-sensitive sodium channel forms ionic channels in lipid bilayers.

A synthetic 22-mer peptide that mimics the sequence of a putative pore segment of the voltage-dependent sodium channel forms transmembrane ionic channels in lipid bilayers. Several features of the authentic sodium channel are exhibited by the synthetic peptide: (i) The single channel conductance of...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Oiki, S, Danho, W, Montal, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279999/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2451248/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.7.2393
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