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Homeostatic competition drives tumor growth and metastasis nucleation

We propose a mechanism for tumor growth emphasizing the role of homeostatic regulation and tissue stability. We show that competition between surface and bulk effects leads to the existence of a critical size that must be overcome by metastases to reach macroscopic sizes. This property can qualitati...

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Detalhes bibliográficos
Main Authors: Basan, Markus, Risler, Thomas, Joanny, Jean-François, Sastre-Garau, Xavier, Prost, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: HFSP Publishing 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799988/
https://ncbi.nlm.nih.gov/pubmed/20119483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2976/1.3086732
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