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Deletion of phospholipase C β4 in thalamocortical relay nucleus leads to absence seizures

Absence seizures are characterized by cortical spike-wave discharges (SWDs) on electroencephalography, often accompanied by a shift in the firing pattern of thalamocortical (TC) neurons from tonic to burst firing driven by T-type Ca(2+) currents. We recently demonstrated that the phospholipase C β4...

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Main Authors: Cheong, Eunji, Zheng, Yihong, Lee, Kyoobin, Lee, Jungryun, Kim, Seongwook, Sanati, Maryam, Lee, Sukyung, Kim, Yeon-Soo, Shin, Hee-Sup
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799818/
https://ncbi.nlm.nih.gov/pubmed/19955421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912204106
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