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Quantitative imaging of the Dorsal nuclear gradient reveals limitations to threshold-dependent patterning in Drosophila

The NF-κB-related transcription factor, Dorsal, forms a nuclear concentration gradient in the early Drosophila embryo, patterning the dorsal-ventral (DV) axis to specify mesoderm, neurogenic ectoderm, and dorsal ectoderm cell fates. The concentration of nuclear Dorsal is thought to determine these p...

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Autors principals: Liberman, Louisa M., Reeves, Gregory T., Stathopoulos, Angelike
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799780/
https://ncbi.nlm.nih.gov/pubmed/20018754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906227106
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