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Planarian Hedgehog/Patched establishes anterior–posterior polarity by regulating Wnt signaling

Despite long-standing interest, the molecular mechanisms underlying the establishment of anterior–posterior (AP) polarity remain among the unsolved mysteries in metazoans. In the planarians (a family of flatworms), canonical Wnt/β-catenin signaling is required for posterior specification, as it is i...

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Detalhes bibliográficos
Main Authors: Yazawa, Shigenobu, Umesono, Yoshihiko, Hayashi, Tetsutaro, Tarui, Hiroshi, Agata, Kiyokazu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799762/
https://ncbi.nlm.nih.gov/pubmed/20018728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907464106
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