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Probing ribosome-nascent chain complexes produced in vivo by NMR spectroscopy

The means by which a polypeptide chain acquires its unique 3-D structure is a fundamental question in biology. During its synthesis on the ribosome, a nascent chain (NC) emerges vectorially and will begin to fold in a cotranslational fashion. The complex environment of the cell, coupled with the gra...

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Autors principals: Cabrita, Lisa D., Hsu, Shang-Te Danny, Launay, Helene, Dobson, Christopher M., Christodoulou, John
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799734/
https://ncbi.nlm.nih.gov/pubmed/20018739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903750106
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