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Using a functional enzyme model to understand the chemistry behind hydrogen sulfide induced hibernation
The toxic gas H(2)S is produced by enzymes in the body. At moderate concentrations, H(2)S elicits physiological effects similar to hibernation. Herein, we describe experiments that imply that the phenomenon probably results from reversible inhibition of the enzyme cytochrome c oxidase (CcO), which r...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799705/ https://ncbi.nlm.nih.gov/pubmed/20007376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904082106 |
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