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Hydrogen-Bond Driven Loop-Closure Kinetics in Unfolded Polypeptide Chains

Characterization of the length dependence of end-to-end loop-closure kinetics in unfolded polypeptide chains provides an understanding of early steps in protein folding. Here, loop-closure in poly-glycine-serine peptides is investigated by combining single-molecule fluorescence spectroscopy with mol...

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Détails bibliographiques
Auteurs principaux: Daidone, Isabella, Neuweiler, Hannes, Doose, Sören, Sauer, Markus, Smith, Jeremy C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799665/
https://ncbi.nlm.nih.gov/pubmed/20098498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000645
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