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Effect of Cyclodextrin Complexation on the Aqueous Solubility and Solubility/Dose Ratio of Praziquantel

Praziquantel (PZQ), the primary drug of choice in the treatment of schistosomiasis, is a highly lipophilic drug that possesses high permeability and low aqueous solubility and is, therefore, classified as a Class II drug according to the Biopharmaceutics Classification System (BCS). In this work, β-...

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Detalhes bibliográficos
Main Authors: Maragos, Stratos, Archontaki, Helen, Macheras, Panos, Valsami, Georgia
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799612/
https://ncbi.nlm.nih.gov/pubmed/19949903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9346-7
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