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Mechanisms for increased expression of cholesterol 7α-hydroxylase (Cyp7a1) in lactating rats

Cholesterol 7α-hydroxylase (Cyp7a1) and the bile acid pool size are increased 2–3 fold in lactating postpartum rats. We investigated the interaction of nuclear receptors with the Cyp7a1 proximal promoter and the expression of regulatory signaling pathways in postpartum rats at day 10 (PPd10) vs fema...

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Autori principali: Wooton-Kee, Clavia Ruth, Coy, Donna J, Athippozhy, Antony T, Zhao, Tianyong, Jones, Brett R, Vore, Mary
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799537/
https://ncbi.nlm.nih.gov/pubmed/19957370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23289
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