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Mechanisms for increased expression of cholesterol 7α-hydroxylase (Cyp7a1) in lactating rats

Cholesterol 7α-hydroxylase (Cyp7a1) and the bile acid pool size are increased 2–3 fold in lactating postpartum rats. We investigated the interaction of nuclear receptors with the Cyp7a1 proximal promoter and the expression of regulatory signaling pathways in postpartum rats at day 10 (PPd10) vs fema...

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Detalhes bibliográficos
Main Authors: Wooton-Kee, Clavia Ruth, Coy, Donna J, Athippozhy, Antony T, Zhao, Tianyong, Jones, Brett R, Vore, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799537/
https://ncbi.nlm.nih.gov/pubmed/19957370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23289
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