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Intein-mediated site-specific conjugation of Quantum Dots to proteins in vivo

We describe an intein based method to site-specifically conjugate Quantum Dots (QDs) to target proteins in vivo. This approach allows the covalent conjugation of any nanostructure and/or nanodevice to any protein and thus the targeting of such material to any intracellular compartment or signalling...

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Autori principali: Charalambous, Anna, Andreou, Maria, Skourides, Paris A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799375/
https://ncbi.nlm.nih.gov/pubmed/20003264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3155-7-9
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