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IKK/NF-κB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis

Our understanding of the molecular mechanisms that link inflammation and cancer has significantly increased in recent years. Here, we analyse genetic evidence indicating that the transcription factors nuclear factor-κB (NF-κB) and signal transducer and activator of transcription 3 (STAT3) have a cen...

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Hlavní autoři: Bollrath, Julia, Greten, Florian R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799209/
https://ncbi.nlm.nih.gov/pubmed/19893576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.243
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