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IKK/NF-κB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis

Our understanding of the molecular mechanisms that link inflammation and cancer has significantly increased in recent years. Here, we analyse genetic evidence indicating that the transcription factors nuclear factor-κB (NF-κB) and signal transducer and activator of transcription 3 (STAT3) have a cen...

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Detalhes bibliográficos
Main Authors: Bollrath, Julia, Greten, Florian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799209/
https://ncbi.nlm.nih.gov/pubmed/19893576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.243
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