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An association between Epac-1 gene variants and anxiety and depression in two independent samples

Deficiency in signal transduction might play a role in the development of anxiety and depression, as suggested by a study on the involvement of the PKA-independent Epac pathway. We investigated the association between Epac-1 gene variants, also known as RapGEF-3, and measures of anxiety and depressi...

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Autores principales: Middeldorp, Christel M., Vink, Jacqueline M., Hettema, John M., de Geus, Eco J.C., Kendler, Kenneth S., Willemsen, Gonneke, Neale, Michael C., Boomsma, Dorret I., Chen, Xiangning
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798914/
https://ncbi.nlm.nih.gov/pubmed/19475578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.30976
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