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Deviations from Hardy-Weinberg Equilibrium in Parental and Unaffected Sibling Genotype Data
BACKGROUND: Genotyping error can increase both type I and II errors. In order to elucidate potential genotyping errors, data quality control often includes testing genotype data for deviations from Hardy-Weinberg Equilibrium (HWE). METHODS: The Hardy-Weinberg Disequilibrium (HWD) coefficient and the...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798818/ https://ncbi.nlm.nih.gov/pubmed/19077427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000179558 |
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