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[D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro.

In the search for a more potent bombesin antagonist, we found [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P to be effective in mouse fibroblasts and to inhibit the growth of small cell lung cancer, a tumor that secretes bombesin-like peptides that may act as autocrine growth factors. In murine Swiss 3T3...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Woll, P J, Rozengurt, E
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1988
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC279880/
https://ncbi.nlm.nih.gov/pubmed/2450349
Tagiau: Ychwanegu Tag
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