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Suppression of contractile force in muscle fibers by antibody to myosin subfragment 2.

Polyclonal antibody directed against the subfragment-2 region of myosin was purified by affinity chromatography. Skinned muscle fibers that had been preincubated with antibody were able to sustain only 7% of the active isometric force generated by control fibers. The effect of antibody on force prod...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Lovell, S, Karr, T, Harrington, W F
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1988
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279878/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2964637/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.6.1849
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